Myeloma Bone Disease

This state-of-the-art book presents the forefront in the science and clinical management of myeloma bone disease. Assembling the work of the world's premier thought leaders, this book begins with sections on clinical presentation, imaging, and biochemical markers and then goes on to discuss radiation, surgical, and medical therapies. Specific chapters are devoted to bisphosphonates and novel therapeutic agents, such as RANKL inhibitors, Wnt signaling inhibitors, and IMiDs. The mechanisms of osteoclast activation and osteoblast suppression in multiple myeloma are also explored. "Myeloma Bone Disease" is a valuable resource for medical, surgical, and radiation oncologists and cancer researchers. From the reviews: "This is a highly specialized book dealing with myeloma bone disease. ... The book, authoritative as it is, is likely to be of interest to ... physicians and scientists with a specific interest in myeloma. ... No other book has dealt with the subject of myeloma bone disease in as much depth and, therefore, this one is unique." (Seema Singhal, Doody's Review Service, February, 2011)